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Reza Sheikh Akbari Mehr, Parviz Malekzadeh,
Volume 5, Issue 1 (7-2015)
Abstract

The emergence of new pathogens and the increase in the number of multidrug-resistant strains in well-established pathogens during the past decade represent a growing public health concern globally. Therefore, it is important to introduce and replace new sources of drug such as medicinal plants with antimicrobial properties. The aim of the present sturdy was to evaluate the antibacterial effects of areal parts extract of Epilobium species collected from Iran. The results revealed that extract of all species studied, except (E. roseum subsp. subsessile) could inhibit the growth of bacteria. Based on our results, gram positive test bacteria showed the most susceptibility to the extracts compared to gram negative ones. None of the extracts could affect the growth of Pseudomonas aeruginosa and Enterococcus faecalis. We found that the willow herb extract inhibited the growth of bacteria in culture more effectively than related common antibiotics. Given that aerial parts of plant extract was utilized for this study, further investigation is recommended to determine which specific part of the plant (i.e., leaves, stem, and flowers) possess the antibacterial properties.
Reza Sheikhakbari-Mehr,
Volume 6, Issue 3 (4-2016)
Abstract

Algae are composed of a diverse group of various aquatic organisms. Secondary or primary metabolites from these organisms may be potential bioactive compounds of interest for use in the development of new pharmaceutical agents. In this research, four species of marine algae, Ulva lactuca, Padina pavonica, Colpomenia sinuosa and Cystoseira myrica, isolated from Persian Gulf coasts were evaluated for their antimicrobial activities, using disk diffusion and Minimum Inhibitory Concentration assays. Extracts of the algae selected for this study were prepared using methanol, n-hexane and ethyl acetate as solvents. Best results were shown by the ethyl acetate extracts of Ulva lactuca against bacterial strains. Results also indicated that the bacteria were more sensitive against algal extracts than fungi studied. The lowest value for MIC test was belonged to the green alga, Ulva lactuca, in accordance with growth inhibition zone values obtained from disk diffusion assay. Based on present results, gram-positive bacteria were more sensitive to the algal extracts than gram-negative ones.

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